Cowboys vs. Giants odds, line, spread: 2022 Thanksgiving Day NFL picks, predictions by model on 155-109 run

The Dallas Cowboys will look to end their NFL Thanksgiving Day slide when they host the New York Giants in an NFC East battle on Thursday. Dallas (7-3) is 31-22-1 all-time when he plays the Holidays but has lost three straight contests and six of his last eight. The Cowboys achieved a 30-3 win in their only previous matchup against the Giants on Thanksgiving in 1992. New York (7-3) is attempting to record its second win in 12 encounters with Dallas.

Kickoff from AT&T Stadium is scheduled for 4:30 p.m. ET. Dallas is a 10-point favorite in Caesars Sportsbook’s latest Cowboys vs. Giants odds, while the over/under for total points scored is 45.5. Before you hit Giants vs. Cowboys picks, you need to see SportsLine’s Advanced Computer Model NFL predictions and betting recommendations.

The model, which simulates every NFL game 10,000 times, has fetched well over $7,000 for $100 players with top-tier NFL picks since its inception. The model enters Week 12 of the 2022 NFL season with an incredible 155-109 run of top-flight NFL picks, stretching back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch in four of the last six years with straight NFL picks, beating more than 94% of CBS Sports football pick ’em players four times in that span. Whoever followed it is way up.

Now the model has set its sights on Cowboys vs. Giants and just set its picks and Thanksgiving Day NFL predictions. You can now go to SportsLine to see the model selection. Here are some NFL odds and betting lines for Giants vs. Cowboys:

  • Cowboys vs. Giants Spread: Dallas -10
  • Cowboys vs. Giants Over/Under: 45.5 points
  • Cowboys vs. Giants money line: Dallas -455, New York +345
  • DAL: Cowboys are 22-8 against the spread in their last 30 games against division rivals
  • NYG: Giants are 2-9 ATS in their last 11 encounters with Dallas
  • Cowboys vs. Giants selection: See selection here

Featured Game | Dallas Cowboys vs. New York Giants

Why the Cowboys can cover

Dallas has five straight home games with New York and three straight games overall, including a 23-16 win on the road in Week 3. Dak Prescott has been nearly flawless against the Giants lately, throwing 20 touchdown passes and just three interceptions while winning nine straight encounters in the series. The 29-year-old quarterback made four 300-yard passes during the streak and threw at least three touchdown passes five times.

Prescott missed Dallas’ first game against New York this season, but the team rode their ground attack to victory. Tony Pollard hit the first of his three 100-yard streaks that year, gaining 105 on 13 attempts, while Ezekiel Elliott carried 15 times for 73 yards and a touchdown. A two-time NFL rushing leader, Elliott amassed 1,013 scrimmage yards and 10 total TDs in 11 career contests against the Giants. See which team you should pick here.

Why the Giants can cover

New York will need another strong effort from Daniel Jones against a Cowboys defense that ranks first in the NFL against pass (174.5 yards allowed). The 25-year-old quarterback had just his second 300-yard pass since the start of the 2020 season last week, throwing for 341 against the Lions. Jones also led the team in rushing with 50 yards on seven carries, marking the fourth time this year that he has reached the mark while recording both a passing and a rushing touchdown.

The Giants will also need a bounce back outing from Saquon Barkley, who started last week as the league’s leading rusher but was limited to 22 yards on 15 carries. The 25-year-old, who is 47 yards from his third 1,000-yard season, is second in rushing and first with 1,163 scrimmage yards. Barkley accumulated 126 of those against Dallas in Week 3, winning 81 from 14 carries and 45 from four receptions. See which team you should pick here.

How to do Cowboys vs. Giants picks

SportsLine’s model is based on total points and calls for 46 combined points. The model also says that one side of the spread has all the value. You can only see the model’s NFL picks at SportsLine.

So who will win on Thanksgiving Day Giants vs. Cowboys? And which side of the spread has all the value? Visit SportsLine now to see which side of the Cowboys vs. Giants spread to jump to, all from the model on a 155-109 roll on NFL picks, and find out.


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